Affiliation:
1. Biozentrum, Universität Basel, 4056 Basel, Switzerland.
Abstract
Size determination represents a fundamental requirement for multicomponent biological structures. Some pathogenic bacteria possess a weapon derived from the flagellum. Like the flagellum, this type-III secretion apparatus, called the injectisome, has a transmembrane basal body, but the external component is a needle-like structure instead of a hook and a filament. Here, we provide evidence that the length of this needle is determined by the size of a protein, YscP, acting as a molecular ruler.
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
256 articles.
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