Molecular-Level Functional Magnetic Resonance Imaging of Dopaminergic Signaling-Reference-Cited by-同舟云学术

Molecular-Level Functional Magnetic Resonance Imaging of Dopaminergic Signaling

Published:2014-05-02 Issue:6183 Volume:344 Page:533-535
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Lee Taekwan¹,Cai Lili X.¹,Lelyveld Victor S.¹,Hai Aviad¹,Jasanoff Alan¹²³

Affiliation:

1. Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.

2. Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA.

3. Department of Nuclear Science and Engineering, MIT, 77 Massachusetts Avenue, Room 16-561, Cambridge, MA 02139, USA.

Abstract

Watching Brain Molecules Functional neuroimaging using magnetic resonance imaging (MRI) molecular sensors would be useful for mechanistic analysis of neural systems. Lee et al. (p. 533 ) applied MRI-detectable sensors to measure molecular aspects of brain function in conjunction with noninvasive imaging. The molecular sensor revealed a quantitative spatiotemporal map of dopamine release in the ventral striatum, a brain area involved in processing rewards.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference21 articles.

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3. Behavioral dopamine signals

4. How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

5. Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex

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