Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer-Reference-Cited by-同舟云学术

Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer

Published:2019-01-18 Issue:6424 Volume:363 Page:257-260
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Schuller Jan M.¹^ORCID,Birrell James A.²,Tanaka Hideaki³⁴^ORCID,Konuma Tsuyoshi⁵^ORCID,Wulfhorst Hannes⁶⁷,Cox Nicholas²⁸^ORCID,Schuller Sandra K.⁹^ORCID,Thiemann Jacqueline⁶^ORCID,Lubitz Wolfgang²^ORCID,Sétif Pierre¹⁰^ORCID,Ikegami Takahisa⁵^ORCID,Engel Benjamin D.¹¹,Kurisu Genji³⁴^ORCID,Nowaczyk Marc M.⁶^ORCID

Affiliation:

1. Department of Structural Cell Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

2. Max Planck Institute for Chemical Energy Conversion, 45470 Mülheim an der Ruhr, Germany.

3. Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan.

4. Department of Macromolecular Science, Graduate School of Science, Osaka University, Toyonaka 560-0043, Japan.

5. Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.

6. Plant Biochemistry, Faculty of Biology and Biotechnology, Ruhr University Bochum, 44780 Bochum, Germany.

7. Daiichi Sankyo Deutschland GmbH, Zielstattstr. 48, 81379 München, Germany.

8. Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia.

9. Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor-Lynen-Str. 25, 81377 Munich, Germany.

10. Institut de Biologie Intégrative de la Cellule (I2BC), IBITECS, CEA, CNRS, Université Paris-Saclay, F-91198 Gif-sur-Yvette, France.

11. Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

Abstract

Plugging into the pump Photosynthetic organisms use light to fix carbon dioxide in a process that requires both chemical reducing equivalents and adenosine triphosphate (ATP). Balancing the ratio of these inputs is accomplished by a short circuit in electron flow through photosynthetic complex I, a proton pump that contributes to ATP production but does not increase net reducing equivalents in the cell. Schuller et al. solved a cryo–electron microscopy structure of photosynthetic complex I (see the Perspective by Brandt) and went on to reconstitute electron transfer using the electron carrier protein ferredoxin. Science , this issue p. 257 ; see also p. 230

Funder

Australian Research Council

Deutsche Forschungsgemeinschaft

Max-Planck-Gesellschaft

Ministry of Education, Culture, Sports, Science, and Technology

Core Research for Evolutional Science and Technology, Japan Science and Technology Agency

Osaka University

Agence Nationale de la Recherche

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary