Comment on "Protein Sequences from Mastodon and Tyrannosaurus rex Revealed by Mass Spectrometry"

Author:

Buckley Mike12345,Walker Angela12345,Ho Simon Y. W.12345,Yang Yue12345,Smith Colin12345,Ashton Peter12345,Oates Jane Thomas12345,Cappellini Enrico12345,Koon Hannah12345,Penkman Kirsty12345,Elsworth Ben12345,Ashford Dave12345,Solazzo Caroline12345,Andrews Phillip12345,Strahler John12345,Shapiro Beth12345,Ostrom Peggy12345,Gandhi Hasand12345,Miller Webb12345,Raney Brian12345,Zylber Maria Ines12345,Gilbert M. Thomas P.12345,Prigodich Richard V.12345,Ryan Michael12345,Rijsdijk Kenneth F.12345,Janoo Anwar12345,Collins Matthew J.12345

Affiliation:

1. BioArch, Departments of Biology, Archaeology, Chemistry and Technology Facility, University of York, Post Office Box 373, York YO10 5YW, UK.

2. Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109–0404, USA.

3. Evolutionary Biology Group, Department of Zoology, University of Oxford, OX1 3PS, UK.

4. Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D-04103, Leipzig, Germany.

5. Department of Zoology, Michigan State University, East Lansing, MI 48824, USA.

Abstract

We used authentication tests developed for ancient DNA to evaluate claims by Asara et al . (Reports, 13 April 2007, p. 280) of collagen peptide sequences recovered from mastodon and Tyrannosaurus rex fossils. Although the mastodon samples pass these tests, absence of amino acid composition data, lack of evidence for peptide deamidation, and association of α1(I) collagen sequences with amphibians rather than birds suggest that T. rex does not.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference15 articles.

1. E. Willerslev, A. Cooper, Proc. R. Soc. London. B. Biol. Sci.272, 3 (2005).

2. Protein Sequences from Mastodon and Tyrannosaurus Rex Revealed by Mass Spectrometry

3. M. H. Schweitzer Palaeontologia Electronica 5 editorial 2 (2003); http://palaeo-electronica.org/2002_2/r_and_p.pdf

4. Assessing ancient DNA studies

5. A Basic Mathematical Simulation of the Chemical Degradation of Ancient Collagen

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