Discovery of a Viral NLR Homolog that Inhibits the Inflammasome-Reference-Cited by-同舟云学术

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Discovery of a Viral NLR Homolog that Inhibits the Inflammasome

Published:2011-01-21 Issue:6015 Volume:331 Page:330-334
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Gregory Sean M.¹²,Davis Beckley K.¹,West John A.¹²,Taxman Debra J.¹²,Matsuzawa Shu-ichi³,Reed John C.³,Ting Jenny P. Y.¹²,Damania Blossom¹²⁴

Affiliation:

1. Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.

2. Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.

3. Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

4. UNC Center for AIDS Research, University of North Carolina, Chapel Hill, NC 27599, USA.

Abstract

A viral homolog of a host microbial sensor inhibits viral detection by the host and subsequent antiviral immunity.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Link

http://www.sciencemag.org/content/331/6015/330.full.pdf

Reference29 articles.

1. Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas

2. Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma

3. Immune evasion by Kaposi's sarcoma-associated herpesvirus

4. Olfaction goes digital

5. Intracellular pattern recognition receptors in the host response

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