Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1-Reference-Cited by-同舟云学术

Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1

Published:2011-09-30 Issue:6051 Volume:333 Page:1903-1907
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Refojo Damian¹,Schweizer Martin¹²,Kuehne Claudia¹,Ehrenberg Stefanie¹,Thoeringer Christoph¹,Vogl Annette M.¹,Dedic Nina¹,Schumacher Marion¹,von Wolff Gregor¹,Avrabos Charilaos¹,Touma Chadi¹,Engblom David³,Schütz Günther³,Nave Klaus-Armin⁴,Eder Matthias¹,Wotjak Carsten T.¹,Sillaber Inge¹²,Holsboer Florian¹,Wurst Wolfgang¹⁵⁶⁷,Deussing Jan M.¹

Affiliation:

1. Max Planck Institute of Psychiatry, Munich, Germany.

2. Affectis Pharmaceuticals, Munich, Germany.

3. Division of Molecular Biology of the Cell I, German Cancer Research Center, Heidelberg, Germany.

4. Department of Neurogenetics, Max Planck Institute for Experimental Medicine, Göttingen, Germany.

5. Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany.

6. Technical University Weihenstephan, Institut für Entwicklungsgenetik, Neuherberg, Germany.

7. DZNE-Demenzzentrum, München, Germany.

Abstract

An imbalance between CRHR1-controlled anxiogenic glutamatergic and anxiolytic dopaminergic systems might lead to emotional disturbances.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference29 articles.

1. Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

2. Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse

3. Stress and the brain: from adaptation to disease

4. New approaches to antidepressant drug discovery: beyond monoamines

5. The role of corticotropin-releasing factor in depression and anxiety disorders

Cited by 261 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The diverse role of corticotropin-releasing factor (CRF) and its CRF1 and CRF2 receptors under pathophysiological conditions: Insights into stress/anxiety, depression, and brain injury processes;Neuroscience & Biobehavioral Reviews;2024-08

2. Effects of nanoplastic exposure during pregnancy and lactation on neurodevelopment of rat offspring;Journal of Hazardous Materials;2024-08

3. CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning;Biological Psychiatry;2024-08

4. Cholinergic interneurons in the nucleus accumbens are a site of cellular convergence for corticotropin‐releasing factor and estrogen regulation in male and female mice;European Journal of Neuroscience;2024-07-30

5. Corticotropin-releasing factor and GABA in the ventral tegmental area modulate partner preference formation in male and female prairie voles (Microtus ochrogaster);Frontiers in Neuroscience;2024-07-23