Ethics and Genomic Incidental Findings

Author:

McGuire Amy L.1,Joffe Steven2,Koenig Barbara A.3,Biesecker Barbara B.4,McCullough Laurence B.1,Blumenthal-Barby Jennifer S.1,Caulfield Timothy5,Terry Sharon F.6,Green Robert C.7

Affiliation:

1. Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX 77030, USA.

2. Department of Pediatric Oncology, Dana-Farber Cancer Institute, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02215, USA.

3. Department of Social and Behavioral Sciences, Institute for Health and Aging, Department of Anthropology, History, and Social Medicine, University of California, San Francisco, CA 94143, USA

4. Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA.

5. Health Law Institute, University of Alberta, Edmonton, Alberta T6G 2H5, Canada.

6. Genetic Alliance, Washington, DC 20008, USA.

7. Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Abstract

Laboratories have an obligation to report clinically beneficial incidental findings.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference11 articles.

1. Green R. C. et al.. Genet. Med. (2013); www.acmg.net/docs/ACMG_Releases_Recommendations_on_Incidental_Findings_in_Clinical_Exome_and_Genome_Sequencing.pdf.

2. ACMG Genet. Med. (2013); www.acmg.net/docs/Incidental_Findings_in_Clinical_Genomics_A_Clarification.pdf.

3. Clinical Genome Sequencing

4. The Indispensable Role of Professional Judgment in Genomic Medicine

5. Not-so-incidental findings: the ACMG recommendations on the reporting of incidental findings in clinical whole genome and whole exome sequencing

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