Leveraging Shear Stress to Bust Clots with Nanoparticles-Reference-Cited by-同舟云学术

Leveraging Shear Stress to Bust Clots with Nanoparticles

Published:2012-08-10 Issue:6095 Volume:337 Page:658-659
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Lavik Erin¹,Ustin Jeffrey¹

Affiliation:

1. Case Western Reserve University, Cleveland, OH 44106, USA.

Abstract

Nanoparticle aggregates break apart to release drugs under increased shear stress in blocked blood vessels for improved treatment of stroke, heart attacks, and embolisms.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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5. The t-PA-encapsulated PLGA nanoparticles shelled with CS or CS-GRGD alter both permeation through and dissolving patterns of blood clots compared with t-PA solution: Anin vitrothrombolysis study

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