1. Department of Medicine and Ireland Cancer Center, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH 44106, USA.
2. Department of Biochemistry and Molecular Biology, Medical College of Ohio, Toledo, OH 43699, USA.
3. Johns Hopkins University Oncology Center, 424 North Bond Street, Baltimore, MD 21231, USA.
4. Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, MD 20815, USA