Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor-Reference-Cited by-同舟云学术

Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor

Published:2019-07-12 Issue:6449 Volume:365 Page:162-168
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Ma Leyuan¹²^ORCID,Dichwalkar Tanmay¹^ORCID,Chang Jason Y. H.¹^ORCID,Cossette Benjamin¹,Garafola Daniel¹^ORCID,Zhang Angela Q.¹^ORCID,Fichter Michael¹,Wang Chensu¹^ORCID,Liang Simon¹^ORCID,Silva Murillo¹^ORCID,Kumari Sudha¹^ORCID,Mehta Naveen K.¹³^ORCID,Abraham Wuhbet¹,Thai Nikki¹,Li Na¹,Wittrup K. Dane¹³⁴^ORCID,Irvine Darrell J.¹²³⁵⁶^ORCID

Affiliation:

1. David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

3. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

4. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

5. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

6. Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Funder

National Institutes of Health

Howard Hughes Medical Institute

National Institute of General Medical Sciences

Johnson and Johnson

Deutsche Forschungsgemeinschaft

the Marble Center for Nanomedicine

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference28 articles.

1. Engineered T cells: the promise and challenges of cancer immunotherapy

2. Erratum: The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

3. Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

4. CAR T Cell Therapy for Solid Tumors

5. CAR T cell immunotherapy for human cancer

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