Respiratory homeostasis features in female students with idiopathic arterial hypotension and hyperventilation syndrome

Abstract

Aim. To assess the condition of pulmonary ventilation and diaphragmatic excursion in female students with idiopathic arterial hypotension in the context of hyperventilation syndrome and excessive anxiety. Materials and methods. In total, 62 female students aged 18–24 diagnosed with idiopathic arterial hypotension were examined. The patients were randomly assigned to three groups based on clinical symptoms. Group 1 consisted of 34 students with idiopathic arterial hypotension accompanied by excessive anxiety and hyperventilation syndrome. Group 2 comprised 28 students with arterial hypotension without signs of neurogenic hyperventilation. Group 3, the control one, included 11 apparently healthy age-matched students. The manifestations of hyperventilation syndrome were determined using the Nijmegen Questionnaire. The level of anxiety was assessed using the Spielberger–Hanin scale. Primary indicators of pulmonary ventilation were examined using a Spirolab spirometer (Italy). The diaphragm dynamic function was evaluated by assessing the excursion of its right dome using a Chison QBIT 5 apparatus (China). Results. Through the survey, signs of neurogenic hyperventilation syndrome and excessive anxiety have been identified in the students of Group 1 showing changes in pulmonary ventilation parameters, such as significantly decreased vital capacity (VC), forced vital capacity (FVC), and forced expiratory volume in 1 second (FEV1), compared to the results obtained in Groups 2 and 3, indicating restrictive respiratory disorders. It has been found that diaphragmatic excursion values (18.29 ± 3.26 mm) at rest in Group 1 were significantly lower compared to those obtained in the control group (26.82 ± 2.32 mm) (p ˂ 0.05). During forced breathing, diaphragmatic excursion (56.86 ± 4.35 mm) in Group 1 was lower than that (80.18 ± 3.19 mm) in the control group (p < 0.05). In Group 2, a significant initial decrease in diaphragmatic excursion was revealed only in 26.67 % of the girls. Conclusions. In female students with idiopathic arterial hypotension accompanied by hyperventilation syndrome and excessive anxiety, restrictive pattern of decreased pulmonary ventilation parameters and reduced diaphragmatic excursion were observed.