Twenty-year experience with SPECT/CT in nuclear medicine

Author:

Korol Pavlo1ORCID,Tkachenko Mykola2,Shcherbina Oleg3ORCID

Affiliation:

1. O.O. Bogomolets National Medical University, Kyiv, Ukraine; Kyiv City Clinical Hospital № 12, Kyiv, Ukraine

2. O.O. Bogomolets National Medical University, Kyiv, Ukraine

3. P.L. Shupik National Medical Academy of Postgraduate Education, Kyiv, Ukraine

Abstract

The review discusses the results of twenty years of experience using single-photon emission computed tomography/computed tomography (SPECT/CT). Hybrid imaging, including the use of SPECT in combination with CT, translates molecular and metabolic information directly onto the clinical effect of a wide range of diseases. At the same time, SPECT/CT further improve the diagnostic accuracy, specificity and positive prognostic value of nuclear medicine research. It was considered expedient to carry out a review of modern SPECT/CT applications, not only from the perspective of a diagnostic tool, but to integrate this modality into the clinical process. To this end, complex technological issues are being resolved for attracting new radiopharmaceuticals to use SPECT/CT, improving the quality of protocols for obtaining diagnostic images, quantifying them, as well as compiling protocols for dosimetry and radiation exposure that are beyond the scope of the current review. Key words: single-photon emission computed tomography, hybrid imaging, nuclear medicine, radiopharmaceutical.

Publisher

Institute of Nuclear Medicine and Diagnostic Radiology of the National Academy of Medical Sciences of Ukraine

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference152 articles.

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