Modern approaches to the treatment of radioiodine-refractory differentiated thyroid cancer

Author:

Dzhuzha D.1,Myasoyedov S.2ORCID

Affiliation:

1. National Cancer Institute, Ministry of Health of Ukraine, Kyiv

2. P.L. Shupyk National University of Healthcare of Ukraine, Kiev

Abstract

Radioiodine therapy is the main post-operation method of treatment of advanced differentiated thyroid cancer, but the loss of ability of iodine uptake causes the poor prognosis. The follow-up of patients with radioiodine-refractory differentiated thyroid cancer (RRDTC) is a serious problem. In review the definition, genesis, diagnostics and treatment of RRDTC were revealed. Taking into account the ineffectiveness of traditional methods of redifferentiation therapy, the perspectives of administration of targeted therapies with tyrosine kinase inhibitors were showed. Key words: radioiodine-refractory differentiated thyroid cancer, radioiodine therapy, targeted therapies with tyrosine kinase inhibitors.

Publisher

Institute of Nuclear Medicine and Diagnostic Radiology of the National Academy of Medical Sciences of Ukraine

Subject

General Earth and Planetary Sciences,General Environmental Science

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