Affiliation:
1. National Cancer Institute, Ministry of Health of Ukraine, Kyiv
2. P.L. Shupyk National University of Healthcare of Ukraine, Kiev
Abstract
Radioiodine therapy is the main post-operation method of treatment of advanced differentiated thyroid cancer, but the loss of ability of iodine uptake causes the poor prognosis. The follow-up of patients with radioiodine-refractory differentiated thyroid cancer (RRDTC) is a serious problem. In review the definition, genesis, diagnostics and treatment of RRDTC were revealed. Taking into account the ineffectiveness of traditional methods of redifferentiation therapy, the perspectives of administration of targeted therapies with tyrosine kinase inhibitors were showed.
Key words: radioiodine-refractory differentiated thyroid cancer, radioiodine therapy, targeted therapies with tyrosine kinase inhibitors.
Publisher
Institute of Nuclear Medicine and Diagnostic Radiology of the National Academy of Medical Sciences of Ukraine
Subject
General Earth and Planetary Sciences,General Environmental Science