Radionuclide imaging of arterial inflammation in HIV-infected patients with vascular atherosclerosis-Reference-Cited by-同舟云学术

Radionuclide imaging of arterial inflammation in HIV-infected patients with vascular atherosclerosis

Published:2019 Issue:3 Volume: Page:45-57
ISSN:2707-0700
Container-title:Radiation Diagnostics, Radiation Therapy
language:
Short-container-title:RDRT

Author:

Korol Pavel¹,Shcherbina Oleg²^ORCID

Affiliation:

1. Kyiv City Clinical Hospital № 12, Ukraine

2. P.L. Shupyk National Medical Academy of Postgraduate Education, Kyiv

Abstract

The review examined the role of arterial inflammation in atherogenesis and the pathogenic factors responsible for the high risk of cardiovascular diseases (CVD) among HIV-infected patients. Inflammation has been shown to play an important role in all phases of atherosclerotic CVD. HIV-infected patients have an increased tendency to CVD. The most effective radionuclide method of imaging the inflammatory process in the pathogenesis of CVD among HIV-infected people is F-18 FDG PET/CT. At the present stage, several ligands for visualization were synthesized, which were used to identify vascular inflammation in preclinical and clinical studies. These tracers, in addition to F-18 FDG, have significant potential for future use among HIV-infected patients. Key words: atherosclerosis, cardiovascular disease, positron emission tomography, HIV infection.

Publisher

Institute of Nuclear Medicine and Diagnostic Radiology of the National Academy of Medical Sciences of Ukraine

Subject

General Earth and Planetary Sciences,General Environmental Science

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