This work investigates the relationship between family variables (parents’ educational level, relationship quality, intrusiveness, support, and autonomy) and young Italians’ status as NEETs (Not in Employment, Education, or Training). We used data from a representative sample of 9,087 young Italians. Each participant filled out an anonymous online questionnaire that contained several scales to measure the variables mentioned above. The results reveal that parents’ educational level and support have a protective effect on the risk of becoming a NEET for both genders. Autonomy has a specific negative impact for males while intrusiveness has a positive impact mainly for females.