APPLICATION ANALYSIS OF THE GAMMA-BETA SPECTROMETER MKS-AT1315 TO CONTROL UNWANTED RADIONUCLIDES, FORMED DURING THE PRODUCTION OF RADIOPHARMACEUTICALS

Author:

KIYKO A.1,VABISHCHEVICH S.2,VABISHCHEVICH N.2,BRINKEVICH D.3

Affiliation:

1. Belarusian State Institute of Metrology

2. Euphrosyne Polotskaya State University of Polotsk

3. Belarusian State University

Abstract

Simultaneous measurements of γ- and β-emitting radionuclides in regenerated water and sorption purification cartridges used in the production of radiopharmaceuticals based on 18F were carried out with the MKSAT1315 spectrometer. It was found that the bands observed in the gamma-spectra are due to isotopes of cobalt 55Co, 56Co, 58Co, 57Co, nickel 57Ni, manganese 54Mn and zinc 65Zn, the prospects of using the gamma-beta spectrometer MKS-AT1315 for operational control of the content of undesirable technological radionuclides in the production of radiopharmaceuticals based on 18F are shown.

Publisher

Polotsk State University

Reference10 articles.

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2. Brinkevich, S. D., Brinkevich, D. I., & Kiyko, A. N. (2020). Activation Radionuclides in the Process of Irradiation of a Niobium Target at the Cyclone 18/9 HC Cyclotrone. Physics of Atomic Nuclei, 83(12), 1732–1737. DOI: 10.1134/S1063778820090045.

3. Brinkevich, D. I., Brinkevich, S. D., Vabishchevich, S. A., Krot, V. O., & Maliborskii, A. Ya. (2019). Dolgozhivushchie β-izluchayushchie radionuklidy pri proizvodstve radiofarmpreparatov na osnove 18F [Long-living β-radiating radionuclides in the manufacture of radiopharmatic drugs based on 18F]. Vestnik Polotskogo gosudarstvennogo universiteta. Seriya C, Fundamental'nye nauki [Herald of Polotsk State University. Series С. Fundamental sciences], (4), 67–76.

4. Brinkevich, D. I., Maliborski, A. Ya., & Brinkevich, S. D. (2019). Activation of the cooling circuit water of the Cyclone 18/9-HC cyclotron during the production of 18F. Physics of atomic nuclei, 82(12), 1714–1720. DOI: 10.1134/S1063778819120044.

5. Ivanyukovich, A. A., Soroka, S. A., Krot, V. O., Brinkevich, D. I., Brinkevich, S. D., Chizh, G. V., & Sverdlov, R. L. (2018). Ochistka [18F]ftorida ot dolgozhivushchih radionuklidov pri proizvodstve [18F]ftordezoksiglyukozy [Purification of [18F]fluoride from long-lived radionuclides in production of [18F]fluorodeoxyglucose]. Medicinskaya fizika [Medical Physics], 4(80), 59–65. (In Russ., abstr. in Engl.).

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