Buccal Midazolam Spray as an Alternative to Intranasal Route for Conscious Sedation in Pediatric Dentistry

Abstract

Objectives: To evaluate the acceptance of midazolam spray through buccal route as compared to intranasal route and compare the efficacy of the drug through both the routes. Study Design: 30 patients aged 2-8 years with Grade I or II Frankl's Behaviour Rating Scale were selected who required similar treatment under local anesthesia on two teeth. Midazolam spray was administered randomly through buccal or intranasal routes for the two appointments. Scoring was done for the acceptance of drug and Houpt's score was recorded for the behaviour of patients during the treatment. Results: Acceptance of drug through buccal route was significantly better than the intranasal route (p<0.05) but no statistically significant difference was found in the behaviour scores for the two routes of administration (p≯0.05). Conclusion: Midazolam spray can be effectively used through the buccal mucosa in children who give poor compliance with the intranasal administration.