Housing and Husbandry Alternatives for Naked Mole Rat Colonies Used in Research Settings

Author:

Ragland Natalie H1,Compo Nicole R2,Wiltshire Norman2,Shepard Alyssa3,Troutman Scott3,Kissil Joseph L3,Engelman Robert W2

Affiliation:

1. Department of Biomedical Sciences, Ross University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis, Florida

2. Department of Comparative Medicine, University of South Florida, Tampa, Florida; H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida

3. H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida

Abstract

Naked mole rats (Heterocephalus glaber) are a unique rodent species originating in Africa and are increasingly being used in research. Their needs and characteristics differ from those of other rodents used in research. Unique housing systems are necessary to address the special macro- and microenvironmental requirements of NMRs. Naked mole rats are one of the 2 known eusocial mammalian species, are extremely long-living, are active burrowers, and are accustomed to a subterranean environment. Unlike typical rats and mice, naked mole rats need specific, unique housing systems that mimic their natural subterranean environment to support health and longevity. Here we provide an overview of naked mole rats and a housing method that can be used in research settings.

Publisher

American Association for Laboratory Animal Science

Subject

Animal Science and Zoology

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