A Cross-Sectional Study to Find Out the Relationship of Methylenetetrahydrofolate Reductase (MTHFR) C677T Genotype with Plasma Levels of Folate and Total Homocysteine by Daily Folate Intake in Japanese

Author:

FUKUDA Nana,HAMAJIMA Nobuyuki,WAKAI Kenji,SUZUKI Koji

Publisher

Center for Academic Publications Japan

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference40 articles.

1. 1) Devlin AM, Clarke R, Birks J, Evans JG, Halsted CH. 2006. Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population. Am J Clin Nutr 83: 708-713.

2. 2) Lim U, Wang SS, Hartge P, Cozen W, Kelemen LE, Chanock S, Davis S, Blair A, Schenk M, Rothman N, Lan Q. 2007. Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER Case-Control Study. Blood 109: 3050-3059.

3. 3) Oppeneer SJ, Ross JA, Koh WP, Yuan JM, Robien K. 2012. Genetic variation in folylpolyglutamate synthase and gamma-glutamyl hydrolase and plasma homocysteine levels in the Singapore Chinese Health Study. Mol Genet Metab 105: 73-78.

4. 4) Moat SJ, Lang D, McDowell IFW, Clarke ZL, Madhavan AK, Lewis MJ, Goodfellow J. 2004. Folate, homocysteine, endothelial function and cardiovascular disease. J Nutr Biochem 15: 64-79.

5. 5) Li ZH, Sun L, Zhang HY, Liao YH, Wang DW, Zhao BR, Zhu ZM, Zhao JZ, Ma AQ, Han Y, Wang YB, Shi Y. 2003. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke—A multicenter case-control study in China. Stroke 34: 2085-2090.

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