Chemical Synthesis of a Very Long-Chain Fatty Acid, Hexacosanoic Acid (C26:0), and the Ceramide Containing Hexacosanoic Acid
Author:
Affiliation:
1. Laboratory of Drug Design and Medicinal Chemistry, Showa Pharmaceutical University
Publisher
Center for Academic Publications Japan
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Link
https://www.jstage.jst.go.jp/article/jnsv/61/3/61_222/_pdf
Reference22 articles.
1. 1) Tsuji S, Sano T, Ariga T, Miyatake T. 1981. Increased synthesis of hexacosanoic acid (C26:0) by cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). J Biochem 90: 1233-1236.
2. 2) Koike R, Tsuji S, Ohno T, Suzuki Y, Orii T, Miyatake T. 1991. Physiological significance of fatty acid elongation system in adrenoleukodystrophy. J Neurol Sci 103: 188-194.
3. 3) Antoku Y, Tsukamoto K, Miyoshi Y, Nagino H, Anezaki M, Suwa K, Narabe Y. 2000. Correlations of elevated levels of hexacosanoate in erythrocyte membranes with risk factors for atherosclerosis. Atherosclerosis 153: 169-173.
4. 4) Miyazaki T, Shimada K, Hiki M, Kume A, Kitamura Y, Oshida K, Yanagisawa N, Kiyanagi T, Matsumori R, Daida H. 2014. High hexacosanoic acid levels are associated with coronary artery disease. Atherosclerosis 233: 429-433.
5. 5) Molano A, Huang Z, Marko MG, Azzi A, Wu D, Wang E, Kelly SL, Merrill Jr AH, Bunnell SC, Meydani SN. 2012. Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction. PLoS One 7: e47650.
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