New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives-Reference-Cited by-同舟云学术

New Way of Direct Nitrogen Atom Phenylation in Quinoline Derivatives

Published:2012-07-03 Issue: Volume:2012 Page:1-4
ISSN:2090-5157
Container-title:ISRN Organic Chemistry
language:en
Short-container-title:ISRN Organic Chemistry

Author:

Shchepina Nadezhda E.¹,Avrorin Viktor V.²,Badun Gennady A.³,Lewis Scott B.⁴,Shurov Sergey N.⁵

Affiliation:

1. Laboratory of Radiochemistry, Natural Sciences Institute, Perm State University, Perm 614990, Russia

2. Chemistry Department, Saint Petersburg State University, 26 Universitetsky Pr., Petrodvorets, Saint Petersburg 198504, Russia

3. Radiochemistry Department, M. V. Lomonosov Moscow State University, Leninskie Gory, Moscow 119992, Russia

4. Department of Chemistry, James Madison University, Harrisonburg, VA 22807, USA

5. Department of Organic Chemistry, Perm State University, Perm 614990, Russia

Abstract

Comparison of ion-molecular reactions of free-phenyl cations generated by tritium β-decay with 2-methyl- and 2-phenylquinolines has been investigated. The reaction of direct nitrogen atom phenylation with the help of nucleogenic phenyl cations has been fulfilled for the first time and a new one-step synthesis of tritium-labeled N-phenyl-2-phenylquinolinium salt—lipophilic radioactive biological marker has been elaborated.

Funder

Russian Foundation for Basic Research

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/archive/2012/526867.pdf

Reference19 articles.

1. Pyridine derivatives in the drug arsenal (150 years of pyridine chemistry)

2. TLC Determination of Hydrophilicity Parameter of Some Pyridinium Aldoximes

3. Cationic long-chain ceramide LCL-30 induces cell death by mitochondrial targeting in SW403 cells

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