Constrained Peptides as Miniature Protein Structures-Reference-Cited by-同舟云学术

Constrained Peptides as Miniature Protein Structures

Published:2012-09-26 Issue: Volume:2012 Page:1-15
ISSN:2090-7729
Container-title:ISRN Biochemistry
language:en
Short-container-title:ISRN Biochemistry

Author:

Yin Hang¹

Affiliation:

1. Department of Chemistry and Biochemistry and BioFrontiers Institute, University of Colorado at Boulder, 596 University of Colorado at Boulder, Boulder, CO 80309-0596, USA

Abstract

This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regulations of protein-protein interactions.

Publisher

Hindawi Limited

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

http://downloads.hindawi.com/archive/2012/692190.pdf

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4. Toward Proteomimetics: Terphenyl Derivatives as Structural and Functional Mimics of Extended Regions of an α-Helix

5. Structural Basis for Relief of Autoinhibition of the Dbl Homology Domain of Proto-Oncogene Vav by Tyrosine Phosphorylation

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