Potassium Hydroxide Impregnated Alumina (KOH-Alumina) as a Recyclable Catalyst for the Solvent-Free Multicomponent Synthesis of Highly Functionalized Substituted Pyridazines and/or Substituted Pyridazin-3(2H)-ones under Microwave Irradiation-Reference-Cited by-同舟云学术

Potassium Hydroxide Impregnated Alumina (KOH-Alumina) as a Recyclable Catalyst for the Solvent-Free Multicomponent Synthesis of Highly Functionalized Substituted Pyridazines and/or Substituted Pyridazin-3(2H)-ones under Microwave Irradiation

Published:2011-04-12 Issue: Volume:2011 Page:1-7
ISSN:2090-5149
Container-title:ISRN Organic Chemistry
language:en
Short-container-title:ISRN Organic Chemistry

Author:

Mecadon Hormi¹,Myrboh Bekington¹

Affiliation:

1. Department of Chemistry, North-Eastern Hill University (NEHU), Permanent Campus, Umshing, Mawlai, Shillong 793022, Meghalaya, India

Abstract

The work described herein employs potassium hydroxide impregnated alumina (KOH-alumina) as a mild, efficient, and recyclable catalyst for a one-pot solvent-free and environmentally safer synthesis of 3,4,6-triarylpyridazines and some substituted pyridazines from active methylene carbonyl species, 1,2-dicarbonyls, and hydrazine hydrate by microwave (MW) irradiation. The method offers highly convergent, inexpensive, and functionality-tolerable procedure for rapid access to important pyridazine compounds in good yields.

Funder

University Grants Commission

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/archive/2011/406427.pdf

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