The Sensitization Phase of Allergic Contact Dermatitis Consists of at Least 2 Steps and Its Completion Plays a Crucial Role in the Response to All Antigens

Author:

Kanamori Sachio1,Kaneko Katsumi1,Watari Eiji2,Kawana Seiji1

Affiliation:

1. Department of Dermatology, Nippon Medical School

2. Department of Microbiology and Immunology, Nippon Medical School

Publisher

Medical Association of Nippon Medical School

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference18 articles.

1. 1. Wilson NS, Villadangos JA: Lymphoid organ dendritic cells: beyond the Langerhans cells paradigm. Immunol Cell Biol 2004; 82: 91-98.

2. 3. Phanuphak P, Moorhead JW, Claman HN: Tolerance and contact sensitivity to DNFB in mice. I. In vitro detection by ear swelling and correlation with in vitro cell stimulation. J Immunol 1974; 112: 115-123.

3. 4. Toews GB, Bergstresser PR, Streilein JW, Sullivan S: Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 1980; 124: 445-453.

4. 5. Suzuki K, Kanamori S, Takada K, Kawana S: Divergence of contact hypersensitivity in vivo compared with hapten-specific lymphocyte proliferation and interferon-γ production in vitro following ultraviolet B irradiation: the possibility that UVB does not affect the sensitization phase of contact hypersensitivity. Immunology 2003; 108: 570-578.

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