Generalized myoclonus in two COVID-19 RT-PCR-negative patients with bilateral interstitial pneumonia

Abstract

Introduction: Coronavirus disease 19 (COVID-19) primarily affects the respiratory system. Nevertheless, there are many reports of nervous system involvement and various neurological manifestations affecting the entire neuraxis. The gold standard for diagnosis is considered to be reverse transcriptase polymerase chain reaction (RTPCR) for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). But there is increasing evidence of typical lung involvement and negative RT-PCR results for SARS-CoV-2.