Author:
Sohail Aqib,Amjad Aneela,Zahid Nighat,Chatha Asad Aizaz,Khan Nauman Rauf,Iqbal Aamer,Yusuf Bilal
Abstract
OBJECTIVES:
The current study was conducted to analyze immunohistochemical appearance of P53 protein in odontogenic cysts.
METHODOLOGY:
Thirty paraffin blocks of confirmed case were prepared to investigate the immunohistochemical appearance of P53 protein.
RESULTS:
Sixteen out of thirty odontogenic cysts (53.3%) showed P53, four out of ten dentigerous cyst (40%) had P53, twelve out of fifteen odontogenic keratocysts (80%) expressed P53 while none of the five radicular cysts (0%) showed P53 protein.
CONCLUSION:
Reclassification of OKC as keratocystic odontogenic tumor was supported by the present study and its findings.