Abstract
We will study the influence of low intensity and frequency surface peripheral electrical stimulation (PES) on nerve regeneration of digital nerve injuries of the hand after its surgical repair in humans. Participants will be patients with acute traumatic peripheral nerve injury referred to the Hand Surgery Service of the General Hospital of the State of Bahia, a reference service in the state. These patients will undergo surgery followed by PES in the immediate postoperative period. After hospital discharge, they will be followed up on an outpatient basis by researchers, who will remotely supervise a physiotherapy program. Our hypothesis is that PES will positively influence the recovery of sensory function in patients undergoing neurorrhaphy of digital nerves of the hand. ReBEC registration: U1111-1259-1998 (12/18/2020)
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference68 articles.
1. Electrical stimulation accelerates and increases expression of BDNF and TrKB mRNA in regenerating rat femoral motoneurons.;A Al-Majed;Eur J Neurosci.,2000a
2. Brief electrical stimulation promotes the speed and accuracy of motor axonal regeneration.;A Al-Majed;J Neurosci.,2000b
3. Electrical stimulation accelerates and enhances expression of regeneration-associated genes in regenerating rat femoral motoneurons.;A Al-Majed;Cell Mol Neurobiol.,2004
4. Effect of Ga-As laser on the regeneration of injured sciatic nerves in the rat.;C Bae;In Vivo.,2004
5. A new approach to assess function after sciatic nerve lesion in the mouse - adaptation of the sciatic static index .;A Baptista;J Neurosci Methods.,2007