Elevated shock index and modified shock index are associated with mortality and major adverse cardiac events in patients with acute myocardial infarction: A systematic review and meta-analysis

Author:

Pramudyo MiftahORCID,Putra Iwan Cahyo Santosa,Kamarullah WilliamORCID,Prameswari Hawani SasmayaORCID,Saboe AninkaORCID,Akbar Mohammad Rizki

Abstract

Background Blood pressure (BP) and heart rate (HR) have been studied extensively to predict unfavourable outcomes in patients suffering from an acute myocardial infarction (AMI). Shock index (SI) and modified shock index (MSI) are two new emerging parameters that incorporate BP and HR into their calculations, thereby improving the predictive value of each HR and BP alone in AMI patients. Thus, our aim was to determine the prognostic utility of SI and MSI in AMI patients. Methods We searched PubMed, ProQuest, EBSCO Host, and Europe PMC from conception to May 2022. Studies were eligible if they evaluated the relationship of SI and MSI with all-cause mortality and major adverse cardiac events. Results A total of 16 studies involving 80,195 participants met the inclusion criteria and were included in this meta-analysis. Our study revealed significantly higher all-cause mortality risk for patients with high SI and MSI compared to patients with low indices, regardless of the periods of outcomes, study population, or diverse cut-off values. Moreover, both increased SI and MSI also predicted higher major adverse cardiac events rates. Conclusions According to our findings, both SI and MSI in the emergency department can predict all-cause mortality and major adverse cardiac events in patients with acute myocardial infarction. Given this growing body of evidence, as well as the fact that SI and MSI are very simple objective indices derived from two readily available vital signs, they should be used in daily clinical practice to risk stratify patients presenting with acute myocardial infarction. PROSPER registration CRD42022329558.

Publisher

F1000 Research Ltd

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference50 articles.

1. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines - PubMed.,cited 2022 May 29

2. Mortality From Ischemic Heart Disease|Circulation: Cardiovascular Quality and Outcomes.,cited 2022 May 29

3. Prognostic impact of blood pressure and heart rate at admission on in-hospital mortality after primary percutaneous intervention for acute myocardial infarction with ST-segment elevation in western Romania.;D Bordejevic;Ther. Clin. Risk Manag.,2017

4. Admission heart rate as a predictor of mortality in patients with acute coronary syndromes.;A Timóteo;Acute Card. Care.,2011

5. Shock index: a re-evaluation in acute circulatory failure.;M Rady;Resuscitation.,1992

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