Continuous peritoneal dialysis in pediatric patients with chronic kidney diseases: a case series and literature review

Author:

Sibarani Jupiter,Soetandar AlwinORCID

Abstract

Background: Continuous ambulatory peritoneal dialysis (CAPD) is still a viable option for pediatric renal replacement therapy in both acute and chronic conditions. In a country with limited resources, CAPD is still the treatment of choice for pediatric patients with end stage chronic kidney disease (CKD). Case presentation: We present a case series of six children with chronic kidney diseases on continuous ambulatory peritoneal dialysis (CAPD (age range: 10–16 years old). All patients were diagnosed with CKD stage 5. Of the six patients, four were diagnosed with nephrotic syndrome, one with systemic lupus erythematosus with kidney involvement, 1 with primary glomerulopathy, and one was diagnosed with congenital anomaly of a kidney. In this study, most patients experienced infection as the side effect of CAPD (n = 4; 66.67%), while the remainings experienced adhesion (n = 2; 33.33%). CAPD was effective in 4 of 6 patients who received the device. Discussion: Due to the emergence of complications, the lack of long-term efficacy of CAPD is the most significant factor limiting its application. Conclusion: The authors report a case series of successful experience with CAPD in children with CKD in Indonesia. Although CAPD is effective, the majority of patients in this series do not survive.

Publisher

F1000 Research Ltd

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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