Abstract
Few reports in the literature document acute taste disturbance following exposure to toxic chemicals. We describe the case of a 54-year-old man who presented with primary complaint of tongue numbness and persistent problems with taste 1.5 years following oral exposure to a commercial cleaning agent. A test of olfaction revealed normosmia for age and gender. Lingual tactile two-point discrimination testing showed reduced somatosensation. Taste threshold testing using a 3-drop method demonstrated severe hypogeusia, though the patient was able to discriminate tastants at lower concentrations with a whole mouth swish and spit test. We conclude that clinical evaluation of dysgeusia can be performed using a number of previously published testing methods, however, determining causative factors may be confounded by duration since exposure, lack of knowledge of baseline taste function, and medications. Although many testing options exist, basic taste testing can be performed with minimal expertise or specialized equipment, depending on the patient history and goals of evaluation.
Funder
National Institutes of Health
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference33 articles.
1. Neurological causes of taste disorders.;J Heckmann;Adv Otorhinolaryngol.,2006
2. Olfactory and gustatory functions in bipolar disorders: A systematic review.;F Kazour;Neurosci Biobehav Rev.,2017
3. Tastes associated with parenteral chemotherapy for breast cancer.;J Fetting;Cancer Treat Rep.,1985
4. Toxin-induced chemosensory dysfunction: a case series and review.;W Smith;Am J Rhinol Allergy.,2009
5. Burning mouth syndrome.;M Grushka;Adv Otorhinolaryngol.,2006
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