Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact
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Published:2023-10-24
Issue:
Volume:12
Page:1401
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ISSN:2046-1402
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Container-title:F1000Research
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language:en
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Short-container-title:F1000Res
Author:
Jungbluth StefanORCID, Martin WilliamORCID, Slezak Monika, Depraetere Hilde, Guzman Carlos A.ORCID, Ussi Anton, Morrow David, Van Heuverswyn Fran, Arnouts SvenORCID, Carrondo Manuel J. T., Olesen Ole, Ottenhoff Tom H.M., Dockrell H. M., Ho Mei Mei, Dobly Alexandre, Christensen Dennis, Segalés Joaquim, Laurent Fabrice, Lantier Frédéric, Stockhofe-Zurwieden Norbert, Morelli Francesca, Langermans Jan A.M.ORCID, Verreck Frank A.W., Le Grand Roger, Sloots Arjen, Medaglini Donata, Lawrenz Maria, Collin Nicolas
Abstract
Background Research infrastructures are facilities or resources that have proven fundamental for supporting scientific research and innovation. However, they are also known to be very expensive in their establishment, operation and maintenance. As by far the biggest share of these costs is always borne by public funders, there is a strong interest and indeed a necessity to develop alternative business models for such infrastructures that allow them to function in a more sustainable manner that is less dependent on public financing. Methods In this article, we describe a feasibility study we have undertaken to develop a potentially sustainable business model for a vaccine research and development (R&D) infrastructure. The model we have developed integrates two different types of business models that would provide the infrastructure with two different types of revenue streams which would facilitate its establishment and would be a measure of risk reduction. For the business model we are proposing, we have undertaken an ex ante impact assessment that estimates the expected impact for a vaccine R&D infrastructure based on the proposed models along three different dimensions: health, society and economy. Results Our impact assessment demonstrates that such a vaccine R&D infrastructure could achieve a very significant socio-economic impact, and so its establishment is therefore considered worthwhile pursuing. Conclusions The business model we have developed, the impact assessment and the overall process we have followed might also be of interest to other research infrastructure initiatives in the biomedical field.
Publisher
F1000 Research Ltd
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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