Advances in the understanding and clinical management of mastocytosis and clonal mast cell activation syndromes

Author:

González-de-Olano David,Matito Almudena,Orfao Alberto,Escribano Luis

Abstract

Clonal mast cell activation syndromes and indolent systemic mastocytosis without skin involvement are two emerging entities that sometimes might be clinically difficult to distinguish, and they involve a great challenge for the physician from both a diagnostic and a therapeutic point of view. Furthermore, final diagnosis of both entities requires a bone marrow study; it is recommended that this be done in reference centers. In this article, we address the current consensus and guidelines for the suspicion, diagnosis, classification, treatment, and management of these two entities.

Publisher

F1000 Research Ltd

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference124 articles.

1. Generation of anaphylatoxins by human beta-tryptase from C3, C4, and C5.;Y Fukuoka;J Immunol.,2008

2. Basophils and mast cells: morphologic insights into their biology, secretory patterns, and function.;S Galli;Prog Allergy.,1984

3. The high affinity receptor for IgE on mast cells.;H Metzger;Clin Exp Allergy.,1991

4. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.;D Arber;Blood.,2016

5. Flow cytometric analysis of mast cells from normal and pathological human bone marrow samples: identification and enumeration.;A Orfao;Am J Pathol.,1996

Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3