How modelling can help steer the course set by the World Health Organization 2021-2030 roadmap on neglected tropical diseases

Author:

Clark JessicaORCID,Stolk Wilma A.ORCID,Basáñez María-GloriaORCID,Coffeng Luc E.ORCID,Cucunubá Zulma M.ORCID,Dixon Matthew A.ORCID,Dyson LouiseORCID,Hampson KatieORCID,Marks MichaelORCID,Medley Graham F.ORCID,Pollington Timothy M.ORCID,Prada Joaquin M.ORCID,Rock Kat S.ORCID,Salje Henrik,Toor JaspreetORCID,Hollingsworth T. DéirdreORCID

Abstract

The World Health Organization recently launched its 2021-2030 roadmap, Ending the Neglect to Attain the Sustainable Development Goals, an updated call to arms to end the suffering caused by neglected tropical diseases. Modelling and quantitative analyses played a significant role in forming these latest goals. In this collection, we discuss the insights, the resulting recommendations and identified challenges of public health modelling for 13 of the target diseases: Chagas disease, dengue, gambiense human African trypanosomiasis (gHAT), lymphatic filariasis (LF), onchocerciasis, rabies, scabies, schistosomiasis, soil-transmitted helminthiases (STH), Taenia solium taeniasis/ cysticercosis, trachoma, visceral leishmaniasis (VL) and yaws. This piece reflects the three cross-cutting themes identified across the collection, regarding the contribution that modelling can make to timelines, programme design, drug development and clinical trials.

Funder

Bill and Melinda Gates Foundation

UK Department for International Development

MRC Centre for Global Infectious Disease Analysis

UK Medical Research Council

UK Foreign, Commonwealth & Development Office

European and Developing Countries Clinical Trials Partnership (EDCTP2) programme

Publisher

F1000 Research Ltd

Subject

Public Health, Environmental and Occupational Health,Health Policy,Immunology and Microbiology (miscellaneous),Biochemistry, Genetics and Molecular Biology (miscellaneous),Medicine (miscellaneous)

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