Suitable Effective Mode of Administration of Intravenous Ara-C in Acute Leukaemias

Author:

Irshadullah Naseeb Muhammad

Abstract

Abstract: Ara-c is a commonly used drug in acute leukaemias. In different stages of treatment dose and mode of administration of this drug is variable. It is usually considered as a cell cycle specific drug, but except in ‘standard’ induction of remission therapy for acute myelogenous leukaemia it is not usually given by continuous infusion in other conditions. This article discusses about the different intravenous modes of administration of ara-c in AML induction chemotherapy, their outcomes, and urges for trials to find out a suitable mode of administration of this common drug. Keywords: cytosine arabinoside, arabinocytosar, arabinosyl cytarabine, ara-c, cytarabine

Publisher

Haematology Society of Bangladesh

Subject

General Medicine

Reference41 articles.

1. Mohan S, Talbott M, Hande KR. Principles and Pharmacology of Chemotherapy. In: Greer JP, Rodgers GM, Glader B, Arber DA, Means RT Jr., List AF, Appelbaum FR, Dispenzieri A. (eds.) Wintrobe’s Clinical Hematology. 14th ed. Philadelphia, PA: Wolters Kluwer; 2019.

2. Chu E, Laurie JH, Copur MS. Chemotherapeutic and Biologic Drugs. In: Chu E & DeVita VT. (eds.) Physicians’ Cancer Chemotherapy Drug Manual 2021. Massachusetts, MA: Jones & Bartlett Learning; 2022.

3. Gisselbrecht C, Lepage E, Lenoble M, Marty M, Boiron M. Therapy of acute leukemia in the adult. Role of anthracyclins. Pathol Biol (Paris). 1987 Jan;35(1):69-74.

4. Gmür J. Current status of therapy and prognosis in acute adult leukemia. Ther Umsch. 1996 Feb;53(2):111-6.

5. Rowe JM. What is the best induction regimen for acute myelogenous leukemia? Leukemia. 1998 Sep;12 Suppl 1:S16-9.

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