Abstract
In the present study, we explored the predictive value of CRP in patients infected with SARS-CoV-2 omicron variants (omicron patients). 216 omicron patients, comprising 59 ordinary and 157 severe/critical cases, were enrolled in this study. The univariable and multivariate logistical regression revealed that age, neutrophil percentage, lymphocyte percentage, CRP, and complications were independent predictors of disease severity. The area under the ROC curve (AUC) of CRP (0.874) was significantly higher than that of age (0.712), neutrophil percentage (0.729), lymphocyte percentage (0.734), and complications (0.673) in disease severity prediction (all p<0.05). CRP demonstrated a sensitivity of 89.7% and specificity of 78.6% at a cutoff value of 28.17. Thus, CRP could serve as a promising predictor of disease severity in omicron patients.