A comparison of psychosocial interventions for children with cancer and their families in low- and middle-income versus resource-rich developing countries: a systematic review and meta-analysis protocol.

Abstract

Abstract Objectives: The provision of psychosocial care to address stressors accompanying a cancer diagnosis is instrumental in ensuring quality adjusted survival for children with cancer. Availability and delivery of these interventions is largely unknown in low- and middle-income countries (LMICs) and in resources rich developing countries. This systematic review and meta-analysis aims to investigate and compare the published and unpublished reports of psychosocial interventions for children with cancer and their families in LMICs and resources rich developing countries. Results: To be included in this review, studies must explore and report the impact of a psychosocial intervention on physical, mental, psychological and / or long-term health outcomes of children with cancer, their siblings, family members and carers. The impact must be reported or quantified according to a patient and family centered theoretical framework through the patient / family surveys or self-reports. A comprehensive systematic search of relevant databases (PubMed, PsycINFO, Medline, Cochrane, CINAHL and grey literature ProQuest databases) will be carried out using an exhaustive list of search terms to identify all related hits with no language or date restrictions. A pooled effect size will be quantified for the Meta-analysis. This study will bridge a significant existing gap and guide relevant authorities.