Comparison of properties of various modifications of liquid platelet rich fibrin protocols including Sticky bone, PRF block and albumin PRF

Abstract

Abstract BACKGROUND AND OBJECTIVES: Platelet concentrates have been prevalently utilized in regenerative periodontal treatment as they are autologous in nature. PRF block, sticky bone, Alb-PRF, Alb-PRF block are composite materials using PRF and Bone graft, which activate the graft biologically as well as enhance the mechanical properties of the graft. Hence, the present study aims to compare the volumetric change, compressive strength and difference in SEM characteristics of L-PRF, A- PRF, i-PRF, of sticky bone (injectable PRF/i-PRF with a bone graft) and with PRF block (Advanced Platelet Rich Fibrin /A-PRF+ and i-PRF with bone graft), Alb-PRF, Alb-PRF block. METHODOLOGY: Blood specimens were collected from volunteers who were in good overall health and aged between 20 and 50 years. The samples were then subjected for preparation of L-PRF, A- PRF, i-PRF, sticky bone (injectable PRF/i-PRF with a bone graft) and with PRF block (Advanced Platelet Rich Fibrin /A-PRF+ and i-PRF with bone graft), Alb-PRF, Alb-PRF block which were further subjected to assessment of compressive strength, elastic modulus, final volume, degradation time and scanning electron microscopy in triplicates . RESULTS: On comparing, the mean compressive strength of Sticky bone was found to be (304.72±3.05Mpa), that for PRF Block was (256.69±2.12Mpa), Albumin PRF 84.9±3.05MPa and for Albumin PRF block was 187.5±3.75 Mpa The mean modulus of elasticity was found to be 32.66±1.52Mpa in the PRF Block, 27.41±1.03Mpa for Sticky bone, Albumin PRF 16.23±1.52MPa and for Albumin PRF block 16.23±1.52MPa. In the volumetric test, it was found that there was statistically significant increase in the mean volume of L-PRF, A-PRF , i-PRF was 1cm2, PRF Block 1.6cm3, sticky bone 1.2cm3, Alb-PRF 1.2cm3 , and Alb-PRF block was 1.4 cm3 CONCLUSION: The findings of this current research suggest that sticky bone, PRF block, Albumin PRF, and Alb-PRF block all have the potential to substantially improve the degradation time, strength and volume of the graft material.