Abstract
Backgrounds:
Brucellosis is a major public health problem globally, with cases concentrated in working-age populations, but there are few studies on the burden of brucellosis disease in working-age populations. This study estimated the disease burden and spatiotemporal distribution characteristics of brucellosis in Inner Mongolia's working-age population from 2015 to 2020 and explored the ecological influences on its disease burden.
Methods
The study described the incidence of brucellosis in Inner Mongolia's working-age population from 2015 to 2020. It calculated years of life lost with disability (YLD) and the YLD rate. Spatiotemporal Bayesian modeling was utilized; thus, the spatiotemporal variation pattern of brucellosis disease burden was analyzed. Using the geographically weighted regression analysis (GWR), the study explored the ecological influencing factors of the burden of brucellosis in the working-age population.
Results
The incidence rate increased from 30.74/100,000 to 77.29/100,000 in Inner Mongolia's working-age population from 2015 to 2020. The YLD of brucellosis in the working-age population of Inner Mongolia between 2015 and 2020 was 1533.98 person-years, with a YLD rate of 0.091 per 1,000, and the YLD rate exhibited an upward trend with time. The Bayesian spatiotemporal distribution model revealed that the disease burden of Inner Mongolia's working-age population was at high risk and increasing rapidly: areas including Hinggan, Tongliao, and Chifeng. Bayan Nur exhibited a low risk of brucellosis disease burden but a rapid rate of increase. A considerably high number of cattle at year-end (β: 0.011284–0.011290, P < 0.05), low number of beds (β: -0.007465-0.007436, P < 0.05), and high rainfall (β: 0.010495–0.010520, P < 0.05) are ecological influences on the brucellosis disease burden in the working-age population of Inner Mongolia.
Conclusion
From 2015 to 2020, the YLD rate of brucellosis among Inner Mongolia's working-age population exhibited an increasing trend and spatial aggregation. Medical practitioners should dedicate more research attention to areas where the risk of disease burden is growing at a fast rate, and cities with a low risk of disease burden but a fast rate of increase also merit urgent research attention. The number of cattle at year-end, high rainfall, and low number of beds are ecological influences on the brucellosis disease burden among the working-age population.