In-Hospital Complications and Long-term Outcomes of Carotid Artery Stenting: INCARCERATE Study-Reference-Cited by-同舟云学术

In-Hospital Complications and Long-term Outcomes of Carotid Artery Stenting: INCARCERATE Study

Published:2022-08-29 Issue: Volume: Page:
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Author:

Mohebbi Bahram¹,Amiri Faramarz¹,Golmohammadi Neda²,Shishehbor Mehdi H.³,Shafe Omid¹,Moosavi Jamal¹,Sadeghipour Parham¹,Hashemi Gelareh Bani⁴,Zolfaghari Reza¹,Firouzi Ata¹,Hokmabadi Elyar Sadeghi⁵,Bakhshandeh Hooman¹,Ghorbani Askar⁶

Affiliation:

1. Shaheed Rajaei Cardiovascular Medical and Research Center

2. Iran University of Medical Sciences

3. University Hospitals, Cleveland Medical Center, Case Western Reserve University School of Medicine

4. Sina Hospital, Tehran University of Medical Sciences

5. Tabriz University of Medical Sciences

6. Shariati Hospital

Abstract

Abstract Background: One of the most common and treatable causes of stroke is carotid artery stenosis. Carotid artery stenting (CAS) is an option for treating the stenosis, with such notable clinical outcomes as low rates of in-hospital death, stroke, and intracerebral hemorrhage.Methods: All patients who underwent carotid angioplasty between December 2010 and January 2019 in Rajaie Cardiovascular Medical and Research Center were enrolled. The incidence rates of major adverse cardiac and cerebral events (MACCE), defined as a composite of stroke, myocardial infarction, bleeding, and all-cause mortality, both during hospitalization and at long-term follow-up were determined. Results: A total of 380 patients, 264 (69.5%) symptomatic and 116 (30.5%) asymptomatic, were included. The mean age of study population was 68.6 ± 10.6 years. During post-CAS in-hospital course, stroke occurred in 2 (0.5%), intracranial hemorrhage in 4 (1.1%), death in 2 (0.5%) and MACCE in 8 (2.1%) in symptomatic, and stroke in 1 (0.3%), intracranial hemorrhage in 1 (0.3%), death in 1 (0.3%) and MACCE in 3 (0.8%) in asymptomatic patients. Totally, stroke occurred in 3 (0.8%), intracranial hemorrhage in 5 (1.3%), death in 3 (0.8%), and MACCE in 11 (2.89%) patients.Long-term follow-up (40.95 ± 15.81 months) was performed on 295 (77.6%) patients; the results demonstrated a mortality rate of 13.9% (n = 41) which 30 (10.1%) cases belonged to symptomatic and 11 (3.7%) cases were from asymptomatic patients. Stroke happened in 26 (8.8%), that 18 (6.1%) cases were symptomatic and 8 (2.7%) cases were asymptomatic. MACCE rate was 19.3% (n = 57) which 41 (13.8%) cases were symptomatic and 16 (5.4%) were asymptomatic. Age (OR: 1.040, 95% CI: 1.002 to 1.079) was confirmed as a meaningful variable for the occurrence of MACCE. Conclusions: Our results confirm the safety and efficacy of carotid stenting in experienced centers. Age was as an important predictor of all-cause mortality, myocardial infarction, and MACCE.

Publisher

Research Square Platform LLC

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