Affiliation:
1. Sheng Jing Hospital
2. shenyang orthopedic hospital
Abstract
Abstract
Objective
Through the analysis of the measurement data of paravertebral muscle cross-sectional area in normal people and patients with lumbar disease, the change of paravertebral muscle area in patients with lumbar disease was analyzed, and the accurate measurement of paravertebral muscle fat percentage provided a new objective evaluation basis for clinical judgment of lumbar disease.
Methods
The 150 patients with non-specific low back pain(LBP), 150 patients with lumbar disc herniation(LDH) and 150 healthy people were collected. The lumbar MRI was obtained from L3 to L5, and the upper endplate, intervertebral disc and lower endplate were three planes respectively, a total of 9 planes. Image J software was used to measure the area of erector spinae, psoas major muscles, multifidus muscles and fat infiltration area. The degree of LBP was scored by VAS and ODI.
Result
Compared with the normal male group and the female group, the fatty infiltration rate of the female paraspinal muscle is significantly higher than that of the male group, and there is a statistical difference(P < 0.05). There is a linear positive correlation between the fatty infiltration rate of normal paraspinal muscles and age, and the fatty infiltration rate increases significantly with age(P < 0.05). Compared with normal people,the fatty infiltration rate of paraspinal muscles in patients with LDH is significantly increased, and there is a statistical difference(P < 0.05). Compared with normal people, the fatty infiltration rate of paraspinal muscle in patients with LBP was significantly increased, and there was statistical difference(P < 0.05). There was a correlation between VAS score, ODI score and the fatty infiltration rate in patients with LBP, and the fatty infiltration rate gradually increased with the increase of score(P < 0.05).
Conclusion
In normal subjects, the fatty infiltration rate of paraspinal muscle was higher in female ,and the fatty infiltration rate of paraspinal muscle increased with age. Patients with LDH have a greater rate of fatty infiltration than normal subjects. The rate of fatty infiltration of patients with LBP is also higher than that of normal subjects, and the higher the VAS score and ODI score, the higher the fatty infiltration rate.
Publisher
Research Square Platform LLC
Reference38 articles.
1. The stabilizing system of the spine. Partâ
. Function, dysfunction, adaption, and enhancement;Panjabi MM;J Spinal Disord,1992
2. MRI of paraspinal muscles in lumbar degenerative kyphosis patients and control patients with chronic low back pain;Kang CH;Clin Radiol,2007
3. Research Progress of Non-specific Low Back Pain Assessment Scale, Pathogenesis and Diagnosis and Treatment;Shengyan Duan,Yunlong Zhao,Guangchao Chen;Prev Med,2017
4. Effect of endoscopic technique on lumbar function and pain in patients with lumbar disc herniation;He Liu B;Mod diagnosis Treat,2017
5. Expression and Purification of Active ï¼²ecombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli;Krishnan B;Methods Mol Biol,2017