The Effect of Blood Purification Combined with Psychological Care on Children with Amanita Phalloides Poisoning: A Retrospective Study

Abstract

Abstract Background: Amanita phalloides poisoning is a life-threatening condition that can cause acute liver failure, coagulopathy, and multi-organ failure. Blood purification treatment and nursing care are essential for managing this poisoning. However, there is a lack of systematic comparison of the effects of different blood purification methods and nursing techniques on the prognosis and quality of life of patients with Amanita phalloides poisoning. Methods: We conducted a retrospective observational study of 43 patients with Amanita phalloides poisoning who were admitted to the PICU of a tertiary hospital from January 2019 to December 2021. We collected and analyzed their demographic and biochemical data, blood purification treatment, nursing method, and outcome. We also assessed the psychological state and quality of life of 3-year-old children using the Child Behavior Checklist (CBCL) before and after treatment. Results: Blood purification treatment significantly improved the biochemical indicators and patient outcomes. Intensive and psychological care assistance reduced the average recovery time and increased the proportion of improved patients. Psychological care assistance also improved the psychological state of 3-year-old children. No significant differences in biochemical indicators existed between male and female patients before treatment. Prothrombin time and blood ammonia levels varied significantly by age before treatment. Conclusions: Our study suggests that blood purification treatment effectively removes toxins and improves liver function and coagulation status in patients with Amanita phalloides poisoning. Intensive care and psychological care assistance can enhance the physical and mental health of the patients and promote their recovery. We recommend a comprehensive treatment and nursing program to improve patients' prognosis and quality of life with Amanita phalloides poisoning.