Affiliation:
1. University of Medicine and Pharmacy Ho Chi Minh City
Abstract
Abstract
Background: Kimura disease (KD) is a rare benign chronic inflammatory condition that predominantly affects Asian males. It is characterized by subcutaneous tissue masses in the head and neck region, enlarged lymph nodes, increased blood eosinophilia, and elevated serum total IgE levels. In this report, we describe a rare case of KD in a young Vietnamese female.
Case summary: A 31-year-old Vietnamese woman presented to the hospital with 2 masses in the bilateral cheeks and 1 mass behind the left ear that persisted for 15 years, recurrent skin itching, elevated serum total IgE levels and increased blood eosinophilia. No medical history of the individual or family was recorded. We performed an excision biopsy of the postauricular mass which revealed follicular hyperplasia with small vessel hyperplasia, diffuse infiltration of eosinophils in lymphoid follicles, and several eosinophilic microabscesses. After a comprehensive review, the final diagnosis for this patient was KD and atopic dermatitis comorbidity.
Conclusion: KD is not limited to males, as this report demonstrated. The histopathological examination plays an important role in the diagnosis of KD. This case illustrated the characteristic description of KD and highlights the need for awareness of this rare disease in Asian women.
Publisher
Research Square Platform LLC
Reference19 articles.
1. Eosinophilic hyperplastic lymphogranuloma, comparison with Mikulicz’s disease;Kim HSC;Chin Med J,1937
2. On the unusual granulation combined with hyperplastic changes of lymphatic tissues;Kimura TYS;Trans Soc Pathol Jpn,1948
3. Kimura disease in the parotid gland;Uysal IO;J Craniofac Surg,2011
4. Kimura's disease. Diagnosis by aspiration cytology;Deshpande AH;Acta Cytol,2002
5. Increase of Th2 and Tc1 cells in patients with Kimura's disease;Ohta N;Auris Nasus Larynx,2011