Abstract
In this case, contezolid was successfully used to treat a centenarian male patient with a Vancomycin-resistant Enterococci induced biliary tract infection. Treatment was initiated with contezolid 800 mg every 12 hours for 14 days instead of linezolid due to a significant decrease in platelet count. After treatment, the patient's temperature normalized, the infection was effectively controlled, and organ function improved. There were no reports of infection recurrence or drug-related adverse reactions during a three-month follow-up period. This experience demonstrates the effectiveness and safety of contezolid in managing biliary tract infections.