Affiliation:
1. Rodaki Institute of Higher Education
2. Cardiff University, Cardiff University School of Medicine
3. Shiraz University of Medical Sciences
4. International School of Medicine, Istanbul Medipol University
5. Superior School of Health Sciences
6. University of Pisa
7. Medical Park Ankara Hospital
8. Mus State Hospital
Abstract
Abstract
Symptoms of cognitive and motor impairments are the most important factors when considering children with cerebral infarction and polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome.
Purpose
What factors are important between POEMS Syndrome and ischemic stroke? Are there novel diagnostics for reducing stroke incidence in POEMS Syndrome?
Method
An observational study comprised 100 patients without CT or MRI and 340 multilingual participants with CT and MRI. All relevant behavior and demographic information were recorded. Per the familial history of POEMS Syndrome, we selected one teenager with cerebral infarction and visual cognition.
Result
A few studies have used a representative sample of children with cerebral disorders in which all patients were investigated separately. Occasionally, severe motor impairment in children is often suggested but not investigated, while cognitive impairment was evident among this populace. Thus, it is advised and required to conduct long-term neuropsychological studies that consider not just interventional studies but also very young cohorts with severe speech and movement disorders alongside visual cognitive issues as failure in the evaluation may overestimate the prevalence of mental disorder.
Conclusion
The endocrine system's role in neurocognition and neuroplasticity behavior is distinct. Clinical educators must maintain the multifaceted interplay between gender, hormones, dosage, exposure time, and brain structure. These complex implications are moving the field of neuroendocrinology with exciting new concepts.
Publisher
Research Square Platform LLC
Reference39 articles.
1. POEMS syndrome: update on diagnosis, risk-stratification, and management;Dispenzieri A;Am J Hematol,2015
2. Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature;Bardwick PA;Medicine (Baltimore),1980
3. Multiple vascular abnormalities and a paradoxical combination of vitamin B12 deficiency and thrombocytosis in a case with POEMS syndrome;Lewerenz J;J Neurol,2003
4. Haider S, Ahmad N, Anaissie EJ, Abdel Karim N. Atypical B12 deficiency with nonresolving paraesthesia. Case Rep Oncol Med. 2013; 2013:823–842.
5. Yin H, Zhang L, Pan B, Zhao J, Feng J, Li J. Cerebral thrombotic event as a rare complication in a young female patient with idiopathic multicentric Castleman disease. Clin Neurol Neurosurg. 2020 Nov;198:106246. doi: 10.1016/j.clineuro.2020.106246. Epub 2020 Oct 5. PMID: 33032104.