Evaluation of a neem (Azadirachta indica) herbal formulation for management of sarcoptic mange in dromedary camels

Author:

Atal Tej Prakash1,Narnaware Shirish Dadarao2ORCID,Choudhary Sunita1,Sawal Rajesh Kumar2,Ranjan Rakesh2

Affiliation:

1. College of Veterinary and Animal Science Bikaner

2. ICAR-National Research Centre on Camel

Abstract

Abstract In dromedary camels sarcoptic mange is a highly contagious zoonotic mite infection. In the present study, a neem herbal formulation was prepared using fresh neem leaves, mustard oil, turmeric powder, camphor oil and distilled water for treatment of sarcoptic mange in adult dromedary camels. Total seven applications of this formulation was applied in six mange affected camels at every alternate day. The efficacy of this formulation was compared with six camels receiving two doses of ivermectin injection (dose rate 0.2mg/Kg body weight) at 7 days interval. To evaluate the therapeutic efficacy of the formulation, improvement in skin lesions of mange were recorded, and skin scraping and skin biopsy examination was performed before and after treatment. Macroscopically all the mange affected camels showed grey colored dry skin lesions over different body parts with intense pruritus, alopecia, thickening and corrugation. At the end of treatment trial, the neem formulation treated camels showed complete recovery without any remnants of scar or keratinization at affected sites, further the skin became smooth, shiny and glossy with appearance of new hair growth. In ivermectin treated camels although recovery from mange lesions was observed after 14th day, however the grey areas of the skin with some remnants of scar or keratinization and patches of alopecia were not completely cured in 50% of the treated camels. The result indicated that neem based herbal formulation have better efficacy than ivermectin against treatment of sarcoptic mange in dromedary camels and can provide a cheap, safe and eco-friendly alternative.

Publisher

Research Square Platform LLC

Reference17 articles.

1. Alemu, S., Bayu Y., Wasihun, P., Abdurahman, A. 2022. Prevalence, phytochemical pnvestigation, and in vitro acaricidal efficacy evaluation of Dodonaea angustifolia, Eucalyptus globulus, Millettia ferruginea, and Euphorbia abyssinica against sarcoptic mange of camel, Babile district, Ethiopia. Journal of Parasitology Research 2022, 8639370. doi: 10.1155/2022/8639370.

2. Hemato-biochemical and therapeutic trials on sarcoptic mange in camels;Aziz PR;International Journal of Current Microbiology and Applied Sciences,2020

3. Bornstein, S., Mörner, T., Samuel, W.M. 2001. Sarcoptes scabiei and sarcoptic mange. In: Parasitic diseases of wild mammals, 3rd Edition, Samuel, W.M., Pybus M.J. and Kocan A.A., eds. Iowa State University Press, Ames, Iowa, USA, 107–119.

4. The effect of ivermectin injection on some clinicopathological parameters in camels naturally infested with scabies;Darwish AA;Advances in Animal and Veterinary Sciences,2020

5. In vitro activity of ten essential oils against Sarcoptes scabiei;Fang F;Parasites and Vectors,2016

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