Correlation between fatty liver index and estimated glomerular filtration rate in an elderly population in Yangzhou, China

Abstract

Abstract OBJECTIVE: To investigate the correlation between fatty liver index (FLI) and estimated glomerular filtration rate (eGFR). METHODS: We analyzed the correlation between fatty liver index (FLI) and estimated glomerular filtration rate (eGFR) in a cohort of elderly people who underwent physical examination at the Medical Examination Center of the Affiliated Hospital of Yangzhou University from 01/01/2020 to 12/31/2020, collected relevant data, and calculated the fatty liver index and estimated glomerular filtration rate. RESULTS: A total of 7879 individuals were included in the analysis, and the results suggested that the probability of abnormal estimated glomerular filtration rate increased in the FLI≥30 group compared to the FLI<30 group, with abnormal estimated glomerular filtration rate of 66.37% and 62.19% in the two groups, respectively (P<0.001). Logistic regression analysis showed that the probability of abnormal estimated glomerular filtration rate increased by 0.7% for every 1 increase in FLI (OR=1.007, 95% CI 1.005-1.010, P<0.001). CONCLUSION: Elevated FLI is associated with an increased risk of abnormalities in their estimated glomerular filtration rate in an elderly population in Yangzhou.