Impact of on-site pharmacists in residential aged care facilities on the quality of medicines use: a cluster randomised controlled trial (PiRACF study)

Author:

Haider Ibrahim1,Kosari Sam1,Naunton Mark1,Niynosenga Theo1,Koerner Jane1,Peterson Gregory2,Davey Rachel1

Affiliation:

1. University of Canberra

2. University of Tasmania

Abstract

Abstract Residents of residential aged care facilities (RACFs) have a high prevalence of use of potentially inappropriate medications (PIMs) and resultant medicines-related harm. This study investigated the effect of an on-site pharmacist model on PIMs use and other medication outcomes for residents in RACFs. A multi-facility, non-blind, cluster randomised controlled trial, with randomisation at the facility level, was conducted. Fifteen facilities enrolled and participated in the study, 7 facilities (560 residents) were allocated to the intervention arm and 8 facilities (737 residents) were allocated to the control arm. Each facility in the intervention arm employed an on-site pharmacist for 12 months to perform medication management activities as part of an interdisciplinary care team. The primary outcome was the proportion of residents taking at least one PIM according to the 2019 Beers® Criteria. Using generalised linear mixed-effects models, accounting for confounders and clustering, there was a significant reduction in the proportion of residents prescribed at least one PIM (odds ratio 0.50, 95% confidence interval, 0.335–0.750; p = 0.001) in the intervention arm. There were also significant decreases in the Anticholinergic Cognitive Burden scale and chlorpromazine equivalent daily dose of antipsychotics. The on-site pharmacist intervention significantly improved the appropriateness of medicines use in RACFs.

Publisher

Research Square Platform LLC

Reference55 articles.

1. Medication safety in residential aged-care facilities: a perspective;Wilson NM;Therapeutic Advances in Drug Safety,2010

2. Adverse Drug Reactions, and Geriatric Syndromes;Shah BM;Clinics in Geriatric Medicine,2012

3. Hajjar, E. R., Cafiero, A. C. & Hanlon, J. T. Polypharmacy in elderly patients. The American Journal of Geriatric Pharmacotherapy 5, 345 – 51 (2007).

4. Pharmaceutical society of Australia. PROGRAM RULES Home Medicines Review. Available at: https://www.ppaonline.com.au/wp-content/uploads/2019/01/HMR-Program-Rules.pdf (2019).

5. Quality Use of Medicines Indicators and Associated Factors in Residential Aged Care Facilities: Baseline Findings from the Pharmacists in RACF Study in Australia;Haider I;Journal of Clinical Medicine,2022

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3