Construction of a predictive model for osteoporosis risk in men: using the IOF one-minute Osteoporosis Test

Author:

Zhang Kun1,Wang Min2,Yi Weihong2,Yang Dazhi2

Affiliation:

1. Health Science Center, Shenzhen University, Shenzhen, 518061, Guangdong, China.

2. Department of Spinal Surgery, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, 518052, Guangdong, China.

Abstract

Abstract Objective To construct a clinical prediction nomogram model using the one-minute IOF osteoporosis risk test as an evaluation tool for male osteoporosis. Methods The one-minute test results and the incidence of osteoporosis were collected from 354 patients in the osteoporotic clinic of our hospital. LASSO regression model and multi-factor Logtisic regression were used to analyze the risk factors of osteoporosis in patients, and the risk prediction model of osteoporosis was established. Verify with an additional 140 objects. Results We used logtisic regression to construct a nomogram model. According to the model, the AUC value of the training set was 0.760 (0.704-0.817). The validation set has an AUC value of 0.806 (0.733-0.879). The test set AUC value is 0.714 (0.609-0.818). The calibration curve shows that its advantage is that the deviation correction curve of the nomogram model can maintain a good consistency with the ideal curve. In terms of clinical applicability, compared with the "total intervention" and "no intervention" schemes, the clinical net return rate of the nomogram model showed certain advantages. Conclusion Using the one-minute osteoporosis risk test provided by IOF, we built a male osteoporosis risk prediction model with good prediction effect, which can provide greater reference and help for clinicians.

Publisher

Research Square Platform LLC

Reference14 articles.

1. J.E. Compston, M.R. McClung, W.D. Leslie, Osteoporosis. Lancet 393, 364–376 (2019)

2. Advancing osteoporosis evaluation procedures: detailed computational analysis of regional structural vulnerabilities in osteoporotic bone;Wysocki MA;J Pers Med,2023

3. J.J. Chamberlain, A.S. Rhinehart, C.F. Shaefer Jr, A. Neuman, Diagnosis and management of diabetes: synopsis of the 2016

4. Pinheiro MB, Oliveira J, Bauman A, Fairhall N, Kwok W, Sherrington C. Evidence on physical activity and osteoporosis prevention for people aged 65 + years: a systematic review to inform the WHO guidelines on physical activity and sedentary behaviour. Int J Behav Nutr Phys Act. 2020;17 LeBoff MS, Greenspan SL, Insogna KL,etl The clinician's guide to prevention and treatment of osteoporosis. Osteoporos Int. 2022;33(10):2049–2102. doi: 10.1007/s00198-021-05900-y. Epub 2022 Apr 28. Erratum in: Osteoporos Int. 2022;: PMID: 35478046; PMCID: PMC9546973. Cherian K.E., Kapoor N., Shetty S., Naik D., Thomas N., Paul T.V. Evaluation of different screening tools for predicting femoral neck osteoporosis in rural south indian postmenopausal women. J. Clin. Densitom. 2018;21:119–124. Kharroubi A, Saba E, Ghannam I, Darwish H. Evaluation of the validity of osteoporosis and fracture risk assessment tools (IOF One Minute Test, SCORE, and FRAX) in postmenopausal Palestinian women. Arch Osteoporos. 2017;12(1):6. doi: 10.1007/s11657-016-0298-8. Epub 2016 Dec 24. PMID: 28013446. Kharroubi A, Saba E, Ghannam I, Darwish H. Evaluation of the validity of osteoporosis and fracture risk assessment tools (IOF One Minute Test, SCORE, and FRAX) in postmenopausal Palestinian women. Arch Osteoporos. 2017;12(1):6. Nguyen T. V., Eisman J. A., Kelly P. J., Sambrook P. N. (1996). Risk factors for osteoporotic fractures in elderly men. American Journal of Epidemiology, 144, 255–263.

5. .IOF.AboutOsteoporosis.https://www.osteoporosis.foundation/patients/about-osteoporosis (2021) Accessed July 1 2021

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3