Abstract
Background This study investigates the mediating role of rumination in the relationship between family function and the fear of disease progression in Ischemic stroke patients. Methods A survey was conducted using a general information questionnaire, Fear of Progression-Questionnaire-Short Form(FoP-Q-SF), Family Assessment Device༈FAD༉, and Chinese Version of Event Related Rumination Inventory(C-ERRI) among 285 Ischemic stroke patients. Results The total score of fear of disease progression in Ischemic stroke patients was (SD = 28.12 ± 9.25). Correlation analysis revealed a negative correlation between fear of disease progression and family function (r = 0.69, P < 0.01), a positive correlation between fear of disease progression and total rumination,the invasive rumination (r = 0.46,0.60, P < 0.01), and an negative correlation between family function and total rumination,invasive rumination(r = 0.38,0.61,P < 0.01). The chain mediation model indicated that family function directly effect on fear of disease progression(β = 0.18,P < 0.01),The direct effect of family function on fear of disease progression had a 95% confidence interval [0.14–0.22].Invasive rumination has a partial mediating effect between family function and fear of disease progression༈β = 0.07,P < 0.01༉, the indirect effect had a 95% confidence interval [0.04–0.10].The proportion of the effect mediated was 28.16%. These results indicate that the partial mediating effect of invasive rumination is significant. Conclusions Fear of disease progression in Ischemic stroke patients is at a moderate level, and invasive rumination significantly mediate the relationship between family function and fear of disease progression.