Affiliation:
1. The Third Affiliated Hospital of Sun Yat-sen University
2. First Affiliated Hospital of Guangzhou University of Chinese Medicine
Abstract
Abstract
PURPOSE: This study aimed to evaluate the safety and efficacy of a rapidly absorbable protein stent during microsurgical vasovasostomy.MATERIALS AND METHODS: Fifty-four rats were randomly divided into control, conventional, and stent groups. The left vas deferens was ligated in the control group and cut with double-layer suturing in the conventional group. The stent group received full-layer suturing with protein stent implantation. Patency rate, sperm quality, and reproductive hormones were evaluated up to 8 weeks. Pathological changes were determined by assessment.RESULTS: Patency rates were similar for the stent and conventional groups (8th week) (p > 0.05). Operation time was lower for the stent group than for the conventional group (p < 0.05). The stent group did not differ significantly from the control or conventional groups in terms of effects on sperm quantity, motility, deformity rate, FSH level, LH level, and testosterone level (p > 0.05).CONCLUSIONS: This study provides a foundation for future studies that may further explore the potential of protein stents in vasovasostomy and other surgical procedures.
Publisher
Research Square Platform LLC
Reference16 articles.
1. Microscopic vasectomy reversal;Silber;Fertility & Sterility,1977
2. Rimar K, Trost L, Brannigan RE. Vasovasostomy techniques for microsurgery specialists, in Microsurgery for Fertility Specialists. Springer; 2013. pp. 49–67.
3. Kavoussi PK. Validation of robot-assisted vasectomy reversal. 2015;17(2):245–7.
4. Marshall MT et al. Robot-assisted vasovasostomy using a single layer anastomosis. 2016.
5. Chan P et al. Pros and cons of robotic microsurgery as an appropriate approach to male reproductive surgery for vasectomy reversal and varicocele repair. 2018. 110(5): p. 816–23.